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{"type":"standard","title":"GABRB3","displaytitle":"GABRB3","namespace":{"id":0,"text":""},"wikibase_item":"Q18025122","titles":{"canonical":"GABRB3","normalized":"GABRB3","display":"GABRB3"},"pageid":14167920,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/0/07/Ideogram_human_chromosome_15.svg/330px-Ideogram_human_chromosome_15.svg.png","width":320,"height":128},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/0/07/Ideogram_human_chromosome_15.svg/474px-Ideogram_human_chromosome_15.svg.png","width":474,"height":189},"lang":"en","dir":"ltr","revision":"1257472489","tid":"f7ce1509-a2f3-11ef-b405-20ba8e6a04f2","timestamp":"2024-11-15T01:50:19Z","description":"Protein-coding gene in the species Homo sapiens","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/GABRB3","revisions":"https://en.wikipedia.org/wiki/GABRB3?action=history","edit":"https://en.wikipedia.org/wiki/GABRB3?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:GABRB3"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/GABRB3","revisions":"https://en.m.wikipedia.org/wiki/Special:History/GABRB3","edit":"https://en.m.wikipedia.org/wiki/GABRB3?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:GABRB3"}},"extract":"Gamma-aminobutyric acid receptor subunit beta-3 is a protein that in humans is encoded by the GABRB3 gene. It is located within the 15q12 region in the human genome and spans 250kb. This gene includes 10 exons within its coding region. Due to alternative splicing, the gene codes for many protein isoforms, all being subunits in the GABAA receptor, a ligand-gated ion channel. The beta-3 subunit is expressed at different levels within the cerebral cortex, hippocampus, cerebellum, thalamus, olivary body and piriform cortex of the brain at different points of development and maturity. GABRB3 deficiencies are implicated in many human neurodevelopmental disorders and syndromes such as Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. The effects of methaqualone and etomidate are mediated through GABBR3 positive allosteric modulation.","extract_html":"
Gamma-aminobutyric acid receptor subunit beta-3 is a protein that in humans is encoded by the GABRB3 gene. It is located within the 15q12 region in the human genome and spans 250kb. This gene includes 10 exons within its coding region. Due to alternative splicing, the gene codes for many protein isoforms, all being subunits in the GABAA receptor, a ligand-gated ion channel. The beta-3 subunit is expressed at different levels within the cerebral cortex, hippocampus, cerebellum, thalamus, olivary body and piriform cortex of the brain at different points of development and maturity. GABRB3 deficiencies are implicated in many human neurodevelopmental disorders and syndromes such as Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. The effects of methaqualone and etomidate are mediated through GABBR3 positive allosteric modulation.
"}{"type":"standard","title":"Nevada State Route 121","displaytitle":"Nevada State Route 121","namespace":{"id":0,"text":""},"wikibase_item":"Q369579","titles":{"canonical":"Nevada_State_Route_121","normalized":"Nevada State Route 121","display":"Nevada State Route 121"},"pageid":5295482,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/0/01/Nevada_121.svg/330px-Nevada_121.svg.png","width":320,"height":320},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/0/01/Nevada_121.svg/600px-Nevada_121.svg.png","width":600,"height":600},"lang":"en","dir":"ltr","revision":"1269757344","tid":"9862a28d-d3d1-11ef-82ae-b486689b8149","timestamp":"2025-01-16T06:17:43Z","description":"Former state highway in Nevada, United States","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Nevada_State_Route_121","revisions":"https://en.wikipedia.org/wiki/Nevada_State_Route_121?action=history","edit":"https://en.wikipedia.org/wiki/Nevada_State_Route_121?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Nevada_State_Route_121"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Nevada_State_Route_121","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Nevada_State_Route_121","edit":"https://en.m.wikipedia.org/wiki/Nevada_State_Route_121?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Nevada_State_Route_121"}},"extract":"State Route 121 was a state highway in Churchill County, Nevada. It spurred from U.S. Route 50, east of Fallon, north 27.05 miles (43.53 km) to a local road, Settlement Road in Dixie Valley, with the moniker of Dixie Valley Road. SR 121 was assigned in 1976 and removed from the primary state highway system in 2021, with the entire length of the route being redesignated as Frontage Road FRCH08.","extract_html":"
State Route 121 was a state highway in Churchill County, Nevada. It spurred from U.S. Route 50, east of Fallon, north 27.05 miles (43.53 km) to a local road, Settlement Road in Dixie Valley, with the moniker of Dixie Valley Road. SR 121 was assigned in 1976 and removed from the primary state highway system in 2021, with the entire length of the route being redesignated as Frontage Road FRCH08.
"}